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iloperidone improves amounts of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on. Iloperidone is often a time-dependent CYP3A inhibitor and should bring on enhanced plasma levels of medicines predominantly eliminated by CYP3A4.A number of plausible but uninvestigated web-sites of action for modafinil, t